Find NHLBI Clinical Trials and Studies
Search selected NHLBI-supported and by condition, location, or age group. You can also view the complete list of NHLBI-funded studies at ClinicalTrials.gov.
Showing 31 - 40 out of 271 results
Recruiting
Michigan
Are you over 18 years old and work nights and work at least 3 night shifts a week? If so, consider joining this study where researchers are testing whether working a night-shift schedule disrupts your ability to get good quality sleep due to stress. The study is taking place in Novi, Michigan.
Adult, Older Adult
Recruiting
Massachusetts
Are you a woman between 18 and 35 years old? This trial is studying how healthy women who have not gone through menopause react to sleep loss at different times during their menstrual cycle. Participants will be exposed to different sleep patterns during the study. The study is taking place in Boston, Massachusetts.
Adult
Accepting Healthy Volunteers
Female
Recruiting
Michigan
Does your child have sleep apnea? To study sleep apnea, researchers use a sleep endoscopy to look at the airway in a sleeping patient. Researchers want to know how two types of anesthesia work during a sleep endoscopy. Your child may be able to join if they are between 3 and 11 years old and need to have their tonsils/adenoids removed. The trial is taking place in Ann Arbor, Michigan.
Child
Recruiting
New York
Have you recently learned you have sleep apnea? If so, you may be able to join this study. Researchers want to see if a medication can help lower the risk of cardiovascular disease in people with sleep apnea. You must be 18 years old. The study is taking place in New York City, New York.
Adult, Older Adult
Recruiting
Maryland
Are you a former smoker with COPD? Researchers are studying whether taking aspirin can help with COPD symptoms. Participants must be at least 40 years old, be diagnosed with COPD, and have a history of smoking at least 10 packs of cigarettes a year. The study is taking place in Baltimore, Maryland.
Adult, Older Adult
Recruiting
Tennessee
Have you been diagnosed with familial hypercholesterolemia (FH)?
Researchers are studying whether a new medicine derived from natural compounds in buckwheat seeds improves the function of “good” HDL cholesterol. To participate in this study, you should be 18 to 69 years old and have been diagnosed with FH. This study is recruiting in Nashville, Tennessee.
Adult, Older Adult
Recruiting
Massachusetts
Do you do shift work and are interested in metabolic health? This study looks at how diet may affect circadian misalignment. To join, you must be 18 to 45 years old and in good health. As a participant, you will stay in the study hospital twice and get all your meals during the study. The study is taking place at Brigham and Women's Hospital in Boston, Massachusetts.
Adult
Accepting Healthy Volunteers
Recruiting
Michigan
Does your child have sleep apnea? Researchers are testing whether a device to help improve airflow in the upper airway can help people with sleep apnea. Participants must be between 3 and 21 years old and have obstructive sleep apnea. The study is taking place in Ann Arbor, Michigan.
Child, Adult
Recruiting
New York
Do you have sickle cell disease? Researchers are testing whether a drug that is often used to treat nausea caused by chemotherapy can also treat chronic pain and improve quality of life in adults living with sickle cell disease. Participants must be between 18 and 80 years old. The study is taking place at Mount Sinai Hospital in New York City.
Adult, Older Adult
Recruiting
Tennessee
Do you have pulmonary arterial hypertension?
Do you have pulmonary arterial hypertension? Increasing physical activity is helpful for people with pulmonary arterial hypertension. Researchers are testing whether sending text messages is an effective way to encourage people with pulmonary arterial hypertension to be more physically active. You must be 18 years old to participate. The study is taking place in Nashville, Tennessee.
The Investigators propose a randomized trial of smart texts versus usual care for 6 months. The Investigators will randomize 100 PAH patients to the mHealth intervention or usual care. The Investigators will test the effect of a text-based mHealth intervention on HRQOL in PAH using the PAH-specific emPHasis-10 questionnaire. The Investigators will also test the effect of an mHealth intervention on exercise capacity, measured by a supervised home-based 6MWD test. Finally, the Investigators will examine the effect of the intervention on time to clinical worsening (composite of PAH therapy escalation, PAH hospitalization, and death) one year after randomization.
The Investigators propose a randomized trial of smart texts versus usual care for 6 months. The Investigators will randomize 100 PAH patients to the mHealth intervention or usual care. The Investigators will test the effect of a text-based mHealth intervention on HRQOL in PAH using the PAH-specific emPHasis-10 questionnaire. The Investigators will also test the effect of an mHealth intervention on exercise capacity, measured by a supervised home-based 6MWD test. Finally, the Investigators will examine the effect of the intervention on time to clinical worsening (composite of PAH therapy escalation, PAH hospitalization, and death) one year after randomization.
Adult, Older Adult